Benefits of an Anti-Relapse Gel-Cream Intended for Very Dry, Irritated to Atopic Sensitive Skin: Results From Clinical Study in Babies, Children and Teenagers in India and Argentina

Atopic Dermatitis (AD) is a chronic, relapsing inflammatory dermatosis related to an altered skin barrier, characterized by eczematous flares, xerosis, and pruritus. Affecting 10 – 25 % of children in industrialized countries,¹ it significantly impairs family quality of life, thereby justifying the integration of adapted dermocosmetic strategies providing intensive anti-pruritic and lipid-replenishing effects. The objective of this clinical study was to evaluate the effectiveness and tolerance of an emollient with active ingredients in a light gel-cream texture to prevent recurrent acute flares of eczema in patients with AD in warm and humid environments.

¹Bylund, S.; von Kobyletzki, L. B.; Svalstedt, M.; Svensson, Å. Prevalence and Incidence of Atopic Dermatitis: A Systematic Review. Acta Derm.-Venereol. 2020, 100, 320–329

This intra-individual and prospective study was conducted in Argentina and India under dermatological control. 46 subjects (4 subjects lost to follow-up) were included, aged 6 months to 15 years, with moderate AD and active eruptions. Subjects received topical treatment (corticosteroids) at inclusion (D0) and had to apply the investigational light gel-cream over their entire body for 120 days, using standardized “3-6-9” method, adjusted for age and body surface area. Several assessments were performed at baseline (D0) and during follow-up visits (D30, D60, D120) including: