Sensibio H2O

• Efficiently and gently cleanses the skin (-99% of make-up, pollutants, and pollens ^(1,2,3))
• Preserves skin ecosystem by limiting TEWL(4) and maintaining microbiome diversity ^(5,6))
• Long-lastingly soothes and reduces unpleasant sensations (-73%* sensation of tightness, -77%* sensation of tingling, -100%* of itching and -73%* of burning ⁽⁷⁾  skin is soothed for 91% of subjects ⁽⁸⁾)

Very good ocular and cutaneous tolerance – Unfragranced

*p<0.001, Wilcoxon test in comparison to D0

(1) Evaluation of foundation removing power on 10 subjects aged from 25 to 49 years old with dry, normal or combination skin by taking picture with VISIA.
(2) Evaluation of capacity of Sensibio H20 to remove microparticles simulating air pollution (PM10, PM2.5, PM1) on 11 subjects aged from 18 to 48 years old with dry or normal skin by taking picture with video microscope.
(3) Evaluation of pollen cleansing power of Sensibio H20 against pollen on 20 subjects aged from 22 to 67 years old with Scanning Electron Microscopy to count the number of pollens. 2019
(4) TEWL and sebum rate measurement on 10 subjects aged from 49 to 69 years old after 4h of application
(5) Evaluation of microbial diversity on 18 subjets aged from 21 to 48 years old by collecting cutaneous microbiota on the backs with swabs, metagenomic analysis to determine the Shannon Index before and after 4 days of using Sensibio H20. 2018
(6) Evaluation of microbial diversity on 20 subjets aged from 24 to 46 years old by collecting cutaneous microbiota on the cheeks with swabs, metagenomic analysis to determine the Shannon Index before and after 28 days of using Sensibio H20. 2020
(7) Evaluation of efficacy and tolerance of Sensibio H20 on 33 subjects with an average age of 36 years with reactive, intolerant, or allergic dry to oily skin after 21 days of twice daily use by clinical scorage and self-assessment. Poland.2018
(8) Self-assessment of cosmetic properties and tolerance of Sensibio H20 on face before and after cosmetic procedure such as laser or peeling on 90 subjects aged from 18 to 71 years old after 28 days of use. Hong-Kong, Taïwan.2014

> CLINICAL RESULTS

Sensibio H20 contains patented Dermatological Advanced Formulation (DAF) complex (patent n°EP1753393) which helps sensitive skin to increase its tolerance threshold.

Sensibio H20 removes 99% of make-up applied on face ⁽¹⁾, 99% of microparticles simulating air pollution ⁽²⁾, 99% of pollen ⁽³⁾ with a global removal efficacy of 78% on 5 heavy metals found in pollution residues ⁽⁴⁾.

Sensibio H20 preserves the skin ecosystem:

• It respects skin barrier function by limiting Transepidermal Water Loss (TEWL) and maintaining sebum rate after 4h of use ⁽⁵⁾
• It respects skin microbiome diversity measured by Shannon Index ^(6,7)

Sensibio H20 also soothes the skin:

• Immediately after use, it significantly decreases the cutaneous temperature by 1.5°C ⁽⁸⁾
• After 21 days of use, it significantly decreases sensation of tightness by 73%*, sensation of tingling by 77%* and itching by 100%* and burning by 73%* ⁽⁹⁾

TOLERANCE
Very high ocular and cutaneous tolerance in sensitive / reactive, intolerant, or allergic skin ^(9,10,12)

***p<0.001, Wilcoxon test in comparison to D0

> PATIENTS FEEDBACKS
Immediately after use, for more than 97% of subjects, skin is cleansed, soft, comfortable, supple, and soothed ⁽¹⁰⁾.

After 28 days of use, Sensibio H20:

• Reduces unpleasant sensations (tightness, tingling, burning and pruritus) for 90% of subjects ⁽¹¹⁾
• Improves quality of life for 77% of subjects  ⁽¹¹⁾
• Soothes the skin for 91% of subjects ⁽¹²⁾ especially after cosmetic procedure ⁽¹³⁾

More than 98.9% of subjects would like to continue using it respectively before and after performing a cosmetic procedure such as laser or peeling to cleanse/remove make-up from the face  ⁽¹³⁾

(1) Evaluation of foundation removing power on 10 subjects aged from 25 to 49 years old with dry, normal or combination skin by taking picture with VISIA. *p<0.05, Student’s test in comparison to a classical cleanser.
(2) Evaluation of capacity of Sensibio H20 to remove microparticles simulating air pollution (PM10, PM2.5, PM1) on 11 subjects aged from 18 to 48 years old with dry or normal skin by taking picture with video microscope.
(3) Evaluation of pollen cleansing power of Sensibio H20 against pollen on 20 subjects aged from 22 to 67 years old with Scanning Electron Microscopy to count the number of pollens..2019
(4) Evaluation of the cleansing power of Sensibio H20 against iron, zinc, chromium, nickel and lead, 5 heavy metals found in pollution residues on 20 subjects aged from 40 to 70 years. 2018
(5) TEWL and sebum rate measurement on 10 subjects aged from 49 to 69 years old after 4h of application.2018
(6) Evaluation of microbial diversity on 18 subjects aged from 21 to 48 years old by collecting cutaneous microbiota on the backs with swabs, metagenomic analysis to determine the Shannon Index before and after 4 days of using Sensibio H20.
(7) Evaluation of microbial diversity on 20 subjects aged from 24 to 46 years old by collecting cutaneous microbiota on the cheeks with swabs, metagenomic analysis to determine the Shannon Index before and after 28 days of using Sensibio H20. 2020
(8) Evaluation of refreshing effect by measurement of cutaneous temperature by thermography on 11 subjects aged from 38 to 72 years old with normal to dry skin immediately after use (from few seconds to 3 minutes).2017
(9) Evaluation of efficacy and tolerance of Sensibio H20 on 33 subjects with an average age of 36 years with reactive, intolerant, or allergic dry to oily skin after 21 days of twice daily use by clinical scorage and self-assessment.Poland.2018
(10) Self-assessment of efficacy and tolerance of Sensibio H20 on 30 subjects aged from 23 to 64 years old with sensitive or fragile skin after 7 days of twice daily use.
(11) Evaluation of Sensibio H20 efficacy on 405 subjects after 28 days of twice daily use by self-assessment on a cell phone application.
(12) Self-assessment of cosmetic properties and tolerance of Sensibio H20 on face before and after cosmetic procedure such as laser or peeling on 90 subjects aged from 18 to 71 years old after 28 days of use. Hong-Kong, Taïwan.2014
(13) Evaluation of cutaneous acceptability by dermatologist on 32 subjects aged from 18 to 62 years old with a contact allergy to at least 2 allergens in the ICDRG standard series. Poland.2015