RESTORES THE MICROBIOME DIVERSITY IN 3H AFTER APPLICATION (1)
SOOTHES ITCHING AND DISCOMFORT SENSATIONS
- 88 % neuronal hyperreactivity via trpv1 pathway (2)
- Promotes re-epithelialization
- +58% keratinocytes proliferation at day 4 (3)
OPTIMAL REPAIR COMPLEX : +88% SKIN REPAIR (4)
A MOIST ENVIRONMENT, ESSENTIAL FOR A GOOD HEALING
+67% the skin is moisturised after 1h (5)
A CLINICALLY PROVEN EFFICACY : VISIBLE IMPROVEMENT AFTER 14 DAYS(6)
-46% red marks (6a), -32% thickness (6a), +45% suppleness* (6a)
* evalutation of the pliability of the skin
(1) Clinical study after disinfection, restoration of Shannon index (diversity and relative abundance of bacteria) 3h post-application of Cicabio Crème+ vs. untreated disinfected zone, on 20 subjects.
(2) In vitro test with Antalgicine™ on co-culture of keratinocytes and sensory neurons stimulated by capsaicin, neuropeptide secretion measurement.
(3) In vitro test on reconstructed skin model, after topical application of Optimal repair vs. untreated.
(4) In vitro study on reconstructed skin model, epidermal closure at D7 after topical application of Optimal repair vs. untreated.
(5) Clinical study on 10 subjects, instrumental measurement after a single application, versus untreated
(6) Clinical study with Cicabio Crème+ on remodeling scars (C-section, episiotomy, adhesions) on 34 subjects, (a) scoring at D14 vs. D0.