A leave-on micellar solution for sensitive skin with dermatological benefits: hydrating, soothing and reducing the burden of skin sensitivity right from the cleansing step

Sensitive Skin Syndrome (SSS) is a common skin condition defined by the occurrence of unpleasant sensations in response to stimuli that normally should not provoke such sensations. It can significantly impact patients quality of life, as symptoms occur immediately following exposure to triggering factors. Taking care of sensitive skin is therefore essential, beginning from the cleansing stage.

Three clinical studies were performed to evaluate the skincare benefits of an ecobiological leave-on micellar solution (MS) (Bioderma, Sensibio H2O) applied on a cotton-pad:

• 20 subjects aged from 26 to 72 years old with sensitive skin used MS on their face twice daily for 28 days. Hydration was measured by corneometry on 10 points distributed on each split-face at D0 and D28 after rinsing or leaving MS, randomly. Values were projected onto an average face model to create a hydration map comparing the rinse-off and leave-on conditions of MS. (single blind study)

• 31 subjects aged from 18 to 66 years old with phototype I to IV, sensitive skin (stinging score ≥ 3) and allergic skin used leave-on MS on their face twice daily for 21 days.

  Tightness, stinging, itching and burning sensations were self-graded by subjects and cutaneous tolerance was evaluated by a dermatologist at D0 and D21. (double blind study)

• 378 subjects in 7 countries, across 4 continents, including pregnant and breastfeeding women, aged from 18 to 75 years old with phototype I to VI used MS twice daily for 21 days. All of them have self-declared sensitive skin, confirmed through an evaluation of the 11-point sensitive scale (SS-10 ≥ 5) and reported a significant burden on their quality of life.

  The impact on quality of life (QoL) was assessed by the Burden Of Skin Sensitivity (BoSS) questionnaire at inclusion (D0) and D21.

  Adverse events were reported by the subjects during the study if noticed (open intra-individual study).

HYDRATES THE SKIN

A hydration map was created to compare hydration variations in different areas after 28 days of twice-daily use:

Hydration increased significantly after 28 days of use, by +15%** for the area where the product was not rinsed-off and by +3% (ns) for the area where the product was rinsed-off, demonstrating the importance of not rinsing off the product.

There was a significant difference between the two treated areas in favor of the non-rinsed area, with +12%* hydration compared to the rinsed area after 28 days of twice-daily use.

ns : not significant, ***p<0.001 Student T-Test vs D0

SOOTHES THE SKIN

Reduction of unpleasant sensations in sensitive and allergic skin

Unpleasant sensations was significantly improved after 21 days of twice-daily use of the micellar solution : 

-79%** global discomfort score

Very good skin and ocular tolerance of the product as determined by dermatologists.

***p<0.001 Wilcoxon test vs D0

IMPROVES QUALITY OF LIFE

The impact of sensitive skin syndrome on daily life decreased on average by -6%** and an improvement was observed in half of the subjects included (50%) after 21 days of using the micellar solution.

According to the BoSS questionnaire, quality of life was significantly improved after 21 days of using the micellar solution.

*p<0.05, **p<0.01, ***p<0.001 Wilcoxon Test vs D0