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A new in vitro method to predict in vivo photoprotection of skin hyperpigmentation induced by visible light

Authors: L. Duteil, B. Cadars, C. Queille-Roussel, I. Giraud, F. Drulhon, C. Graizeau, A. Guyoux, T. Passeron

First published: 28 February 2022

Original Publication from The Journal of the European Academy of Dermatology and Venereology (JEADV), Impact factor (2021): 9.228

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Prof. Thierry Passeron In collaboration with 7 other professionals

5 min read

Ultraviolet radiation is the main cause of skin pigmentation, but more recently visible light has been shown to be an important contributor especially in melano-competent subjects. Photoprotection from visible light can improve several hyperpigmentation disorders. Recently, a visible light photoprotection assessment method has been proposed based on in vivo pigmentation; the visible light photoprotection factor (VL-PF) is determined by assessment of the change in colorimetry parameter ITA over several days measured using a chromameter. Although in vivo methods remain the most representative of real life, in vitro methods are more suited to screening sunscreen formulations.

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