This page is limited to our registered members

Get access to exclusive dermatological services to increase your professionnal knowledge: +500 pathology visuals, clinical cases, expert videos
Benefit from valuable features: audio listening, materials to be shared with your patients
Stay informed about the upcoming events and webinars, latest scientific publications and product innovations

Already have an account? login now

Pure Active Peptide-4 Pro-Collagen 5ppm

All skin types

Face

Smoothes expression wrinkles: -12.2%* in wrinkles count^(1).
IN-SKIN patented technology: diffusion booster to deliver the active ingredient exactly where it needs to go, with a X3 improvement of Pure Active diffusion into the skin^(2).
Suitable for sensitive skin ⁽¹⁾– Very well tolerated ⁽³⁾- Quick penetration and non-oily finish ^(4).

*p<0.05, Wilcoxon test.

Use test under dermatological control, 31 volunteers aged from 40 to 59 years old, 100% sensitive skin, with expression wrinkles on whole face. Twice-daily application, 28 days. Measure of cutaneous relief by Stereo-Fringe projection system+ photography analysis. 2021
Ex-vivo tests on Franz cells: comparison between the diffusion of a standard formula, containing IN-SKIN™ plus 2% caffeine (ingredient selected as example), and the diffusion of a standard formula containing only 2% caffeine (without IN-SKIN™)
Use test under medical supervision (tolerance evaluation), 20 volunteers aged from 36 to 50 years old, all skin types, with expression wrinkles on whole face. Twice-daily application, 28 days. Clinical examination. 2021
Use test under dermatological control, 31 volunteers aged from 40 to 59 years old, 100% sensitive skin, with expression wrinkles on whole face. Twice-daily application, 28 days. Sel-assessment. 2021

Occasional targeted skincare

Pure Active Peptide-4 Pro-Collagen 5ppm

All skin types

Occasional targeted skincare

Pure Active Resveratrol 500ppm

Normal to combination skin

Occasional targeted skincare

Pure Active Retinol 0,3%

All skin types

Occasional targeted skincare

Pure Active Vitamin C 10%

All skin types

> CLINICAL RESULTS

After 28 days of twice-daily application:

Significant reduction of crow's feet wrinkles count ( -12.2%*, by measuring skin relief and analysis resulting photography, -4.8%* in crow’s feet wrinkles score, using the BAZIN grading scale)⁽¹⁾.
Significant smoothing effect: - 13.4%°° of skin texture ⁽²⁾.

> PATIENTS FEEDBACK

After 28 days of twice daily application:

*p<0.05, Wilcoxon test; °°p<0.01, t-test.

Use test under dermatological control, 31 volunteers aged from 40 to 59 years old, 100% sensitive skin, with expression wrinkles on whole face. Twice-daily application, 28 days. Measure of cutaneous relief by Stereo-Fringe projection system+ photography analysis. 2021
Use test under dermatological control, 20 volunteers aged from 36 to 50 years old, all skin type with expression wrinkles. Twice-daily application, 28 days. Measure of cutaneous relief by Stereo-Fringe projection system+ photography analysis. 2021
Use test under dermatological control, 31 volunteers aged from 40 to 59 years old, 100% sensitive skin, with expression wrinkles on whole face. Twice-daily application, 28 days. Self-assessment. 2021

Learn more on Ask NAOS

How should Peptide-4 Pro-Collagen ppm Pure Active for the face be used?

Step 1 Our recommendation: use for 4 weeks as a targeted cure for expression lines.

In the morning and evening, before applying your moisturizing cream (do not mix).
Step 2 Apply to the entire face, concentrating on wrinkles. Apply to dry, thoroughly cleansed skin.
Step 3 Squeeze the base of the bottle and apply 2 drops directly to facial skin, i.e., to each area of concern (wrinkles on the forehead, eye contour area and mouth).

If you are using 2 active ingredients, you may apply one after the other.

For external use.