Pure Active Retinol 0,3%

• Smoothes deep wrinkles: -15%* in wrinkles score ⁽¹⁾ and reported by 94% of volunteers ⁽²⁾.  
• 0.3% of pure Retinol (dose recommended by Scientific Committee on Consumer Safety).
• Very well tolerated ⁽²⁾⁽³⁾ – Non comedogenic ⁽³⁾ – Quick penetration and pleasant to apply ⁽²⁾ - Anhydrous formula with non-oily finish ^(2).

***p<0.0001, Wilcoxon test.

1. Use test under dermatological control, 31 volunteers aged from 38 to 72 years old, all skin types, with wrinkles on face and crow’s feet, with sagging skin. Once-daily application, 28 days. Clinical scoring. 2021 
2. Use test under dermatological control, 32 volunteers aged from 38 to 72 years old, all skin types, with wrinkles on face and crow’s feet, with sagging skin. Once-daily application, 28 days. Self-assessment. 2021 
3. Use test under dermatological control (comedogenic potential and tolerance) performed on 31 subjects aged from 19 to 40 years old, with oily or acne-prone skin. Once-application, for 28 days. 2021

> CLINICAL RESULTS

After 28 days of once-daily use:

• significant reduction in wrinkles’ score (-15%°°°) ⁽¹⁾
• significant increase of firmness’ score (+30%***) ⁽¹⁾.
• significant decrease of Rt parameter (maximum relief amplitude): - 6%*⁽²⁾
• significant decrease of Uf parameter (final deformation): -7%***⁽²⁾

> PATIENTS FEEDBACK

Immediately:

• Retinol 0.3% nourishes the skin (for 100% of subjects) ⁽³⁾.
• Smoothes the skin (for 94% of them) ⁽³⁾.

After 28 days, once-daily application: 

• 97% of subjects mentioned that wrinkles and fine lines are smoothed, skin slackening and signs of photoaging are reduced ⁽³⁾.
• 94% of them found that skin is firmer and deep wrinkles are reduced ⁽³⁾.

°°°p<0.0001, Wilcoxon test; ***p<0.001, t-test; *p<0.05, t-test.   

1. Use test under dermatological control, 31 volunteers aged from 38 to 72 years old, all skin types, with wrinkles on face and crow’s feet, with sagging skin. Once-daily application, 28 days. Clinical scoring. 2021 
2. Use test under dermatological control, 32 volunteers aged from 38 to 72 years old, all skin types, with wrinkles on face and crow’s feet, with sagging skin Once-daily application, 28 days. Measure with Cutometer. 2021
3. Use test under dermatological control, 32 volunteers aged from 38 to 72 years old, all skin types, with wrinkles on face and crow’s feet, with sagging skin. Once-daily application, 28 days. Self-assessment. 2021