3 professionals
Preventing side effects of acne treatments thanks to two specific dermo-cosmetic products
Preventing side effects of acne treatments thanks to two specific dermo-cosmetic products
Fauger A.1, Chavagnac-Bonneville M. 1,2, Graizeau C.1,2 and Sayag M. 1
1NAOS Group, Research and Development Department, Aix-en-Provence, France
2NAOS Institute of Life Science, Aix-en-Provence, France
Related topics
Acne treatments, like keratolytic and isotretinoin treatments, are known to induce many skin side effects like skin barrier alteration and dehydration, potentially leading to poor compliance.
To prevent these side effects and improve compliancy, two specific dermo-cosmetic products were assessed in acne subjects.
In a prospective multicenter clinical study, 106 subjects (mean age 17.8 ± 3.6 years; 81% women) under keratolytic treatment applied since the beginning (D0) of their acne treatment the product S twice a day (morning/evening), and 50 subjects (mean age 19.2 ± 3.4 years; 78% women) under isotretinoin applied the product H once a day (morning). An assessment of the acne severity and the intensity of clinical signs was made at D0. During 28 days the symptoms were evaluated by the subjects as well as the product’s efficacy and tolerability.
The majority of subjects under keratolytic treatment presented a moderate acne (69.8%) and those under isotretinoin presented severe acne (61.2%). Dryness was not exacerbated in both groups and even decreased significantly at D28 with the product S (-33.3%). Similarly, the following criteria were not worsened, and even decreased significantly after 28 days: redness (S: -50.0%; H: -18.8%), burning sensations (-40.0% for both) and tingling sensation (S: -66.7%; H: -46.2%). The subjects evaluated a soothing effect for both products showing a significant increase between D1 and D28 (+33.3% for both), and a significant moisturizing effect (S: +31.3%; H: +19.0%). Overall efficacy was rated good to excellent for 75.2% and 80.0% of subjects with product S and product H, respectively. Both products in association with the corresponding treatment showed good tolerance.
By preventing skin side effects induced by keratolytic and isotretinoin treatment, these two dermo-cosmetic products could increase patients’ compliance to their medical treatment and so their efficacy.
Fauger A.1, Chavagnac-Bonneville M. 1,2, Graizeau C.1,2 and Sayag M. 1
1NAOS Group, Research and Development Department, Aix-en-Provence, France
2NAOS Institute of Life Science, Aix-en-Provence, France
Fauger A., Chavagnac-Bonneville M., and Sayag M.
NAOS, Research & Development Department, Lyon, France
Interest of a cleanser product on subjects with mild to moderate acne and very dry skin due to acne treatments
Create easily your professional account
I create my accountGet access to exclusive dermatological services to increase your professionnal knowledge: +500 pathology visuals, clinical cases, expert videos
Benefit from valuable features: audio listening, materials to be shared with your patients
Stay informed about the upcoming events and webinars, latest scientific publications and product innovations